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For decades, the fight against cancer has been a story of incremental gains. But what if we could teach our own immune systems to become the ultimate weapon against tumors? The groundbreaking success of mRNA vaccines against SARS-CoV-2 has illuminated a powerful new path forward, not just for infectious diseases, but for oncology. Recent studies reveal that this same technology can sensitize even immunologically "cold" tumors to treatment, priming them for destruction by the body's own defenses [1]. Introduction The concept of a cancer vaccine is not new, but early attempts have been hampered by the challenge of generating a sufficiently strong and specific immune response. The advent of mR …