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Anti-C2orf3 Antibody (CAB18388)

SKU:
CAB18388
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€129 - €359
Frequently bought together:

Description

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Antibody Name:Anti-C2orf3 Antibody
Antibody SKU:CAB18388
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human C2orf3.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant protein of human C2orf3.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:6936
Uniprot:P16383
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:C2orf3, DNABF, GCF, TCF9, GCFC2
Background:
UniProt Protein Function:TCF9: Factor that represses transcription. It binds to the GC- rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Belongs to the GCF family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Nucleolus

Chromosomal Location of Human Ortholog: 2p12

Cellular Component: nucleoplasm; nucleolus; nucleus

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; spliceosome assembly; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent

NCBI Summary:The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008]
UniProt Code:P16383
NCBI GenInfo Identifier:318083361
NCBI Gene ID:6936
NCBI Accession:NP_001188263.1
UniProt Secondary Accession:P16383,O95032, Q53TY0, Q6P2F2, A4UHQ8, A4UHQ9,
UniProt Related Accession:P16383
Molecular Weight:28,048 Da
NCBI Full Name:GC-rich sequence DNA-binding factor 2 isoform 2
NCBI Synonym Full Names:GC-rich sequence DNA-binding factor 2
NCBI Official Symbol:GCFC2  
NCBI Official Synonym Symbols:GCF; TCF9; DNABF; C2orf3  
NCBI Protein Information:GC-rich sequence DNA-binding factor 2
UniProt Protein Name:GC-rich sequence DNA-binding factor 2
UniProt Synonym Protein Names:GC-rich sequence DNA-binding factor; Transcription factor 9; TCF-9
UniProt Gene Name:GCFC2  
UniProt Entry Name:GCFC2_HUMAN

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