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Anti-CLEC4G Antibody (CAB10500)

SKU:
CAB10500
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
$167 - $503
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Description

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Antibody Name:Anti-CLEC4G Antibody
Antibody SKU:CAB10500
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 54-293 of human CLEC4G (NP_940894.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Human
Positive Samples:LO2, U-937
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 54-293 of human CLEC4G (NP_940894.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SKAS TERA ALLD GHDL LRTN ASKQ TAAL GALK EEVG DCHS CCSG TQAQ LQTT RAEL GEAQ AKLM EQES ALRE LRER VTQG LAEA GRGR EDVR TELF RALE AVRL QNNS CEPC PTSW LSFE GSCY FFSV PKTT WAAA QDHC ADAS AHLV IVGG LDEQ GFLT RNTR GRGY WLGL RAVR HLGK VQGY QWVD GVSL SFSH WNQG EPND AWGR ENCV MMLH TGLW NDAP CDSE KDGW ICEK RHNC
Gene ID:339390
Uniprot:Q6UXB4
Cellular Location:Cell membrane, Single-pass type II membrane protein
Calculated MW:32kDa
Observed MW:38kDa
Synonyms:CLEC4G, DTTR431, LP2698, LSECtin, UNQ431
Background:This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the T-cell immune response. Multiple transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:CLEC4G: Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner, in vitro. {ECO:0000269|PubMed:14711836}
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: integral to membrane

Molecular Function:protein binding; carbohydrate binding

NCBI Summary:This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the T-cell immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Code:Q6UXB4
NCBI GenInfo Identifier:74738199
NCBI Gene ID:339390
NCBI Accession:Q6UXB4.1
UniProt Related Accession:Q6UXB4
Molecular Weight:32,562 Da
NCBI Full Name:C-type lectin domain family 4 member G
NCBI Synonym Full Names:C-type lectin domain family 4, member G
NCBI Official Symbol:CLEC4G  
NCBI Official Synonym Symbols:LP2698; UNQ431; DTTR431; LSECtin  
NCBI Protein Information:C-type lectin domain family 4 member G; C-type lectin superfamily 4, member G; liver and lymph node sinusoidal endothelial cell C-type lectin
UniProt Protein Name:C-type lectin domain family 4 member G
Protein Family:C-type lectin domain family
UniProt Gene Name:CLEC4G  
UniProt Entry Name:CLC4G_HUMAN
Anti-CLEC4G Antibody (CAB10500)Western blot analysis of extracts of various cell lines, using CLEC4G antibody (CAB10500) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.

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