Anti-DLX1 Antibody (CAB17381)

Antibody Name:	Anti-DLX1 Antibody
Antibody SKU:	CAB17381
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DLX1 (NP_835221.2).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DLX1 (NP_835221.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MTMT TMPE SLNS PVSG KAVF MEFG PPNQ QMSP SPMS HGHY SMHC LHSA GHSQ PDGA YSSA SSFS RPLG YPYV NSVS SHAS SPYI SSVQ SYPG SASL AQSR LEDP GADS EKST VVEG GEVR
Gene ID:	1745
Uniprot:	P56177
Cellular Location:
Calculated MW:
Observed MW:	Refer to figures

Synonyms:

DLX1

Background:

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

UniProt Protein Function:	Plays a role as a transcriptional activator or repressor (PubMed:14671321). Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions.
NCBI Summary:	This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Code:	P56177
NCBI GenInfo Identifier:	84043956
NCBI Gene ID:	1745
NCBI Accession:	NP_001033582.1
UniProt Secondary Accession:	P56177,Q53ZU4, Q7Z724, Q8IYB2, D3DPD7,
UniProt Related Accession:	P56177
Molecular Weight:
NCBI Full Name:	homeobox protein DLX-1 isoform 2
NCBI Synonym Full Names:	distal-less homeobox 1
NCBI Official Symbol:	DLX1
NCBI Protein Information:	homeobox protein DLX-1
UniProt Protein Name:	Homeobox protein DLX-1
Protein Family:	Homeobox protein
UniProt Gene Name:	DLX1

Antibodies

DLX1 Antibody (PACO08858)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)