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Anti-FGL1 Antibody (CAB10977)

SKU:
CAB10977
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
$311 - $431
Frequently bought together:

Description

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Antibody Name:Anti-FGL1 Antibody
Antibody SKU:CAB10977
Antibody Size:50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic Peptide of human FGL1
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:fetal liver
Immunogen:A synthetic Peptide of human FGL1
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:2267
Uniprot:Q08830
Cellular Location:Secreted
Calculated MW:36kDa
Observed MW:36kDa
Synonyms:FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1
Background:Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
UniProt Protein Function:FGL1: Has hepatocyte mitogenic activity.
UniProt Protein Details:

Protein type:Extracellular matrix; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: fibrinogen complex

Biological Process: cholesterol metabolic process

NCBI Summary:Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q08830
NCBI GenInfo Identifier:147744562
NCBI Gene ID:2267
NCBI Accession:Q08830.3
UniProt Secondary Accession:Q08830,Q4PJH9, Q53YF1, Q8NG32, Q96KW6, Q96QM6, A6NKU4
UniProt Related Accession:Q08830
Molecular Weight:312
NCBI Full Name:Fibrinogen-like protein 1
NCBI Synonym Full Names:fibrinogen-like 1
NCBI Official Symbol:FGL1  
NCBI Official Synonym Symbols:HFREP1; HP-041; LFIRE1; LFIRE-1  
NCBI Protein Information:fibrinogen-like protein 1; hepassocin; liver fibrinogen-related protein 1; hepatocellular carcinoma-related sequence; hepatocyte-derived fibrinogen-related protein 1
UniProt Protein Name:Fibrinogen-like protein 1
UniProt Synonym Protein Names:HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; Liver fibrinogen-related protein 1; LFIRE-1
Protein Family:Fibrinogen-like protein
UniProt Gene Name:FGL1  
UniProt Entry Name:FGL1_HUMAN
Anti-FGL1 Antibody (CAB10977)Western blot analysis of extracts of fetal liver, using FGL1 antibody (CAB10977). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

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