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Anti-SLC7A7 Antibody (CAB17586)

SKU:
CAB17586
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€129 - €359
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Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SLC7A7 Antibody
Antibody SKU:CAB17586
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 452-511 of human SLC7A7 (NP_001119577.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 452-511 of human SLC7A7 (NP_001119577.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SGLP FYFL IIRV PEHK RPLY LRRI VGSA TRYL QVLC MSVA AEMD LEDG GEMP KQRD PKSN
Gene ID:9056
Uniprot:Q9UM01
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:LAT3, LPI, MOP-2, Y+LAT1, y+LAT-1, SLC7A7
Background:The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
UniProt Protein Function:Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes.
NCBI Summary:The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
UniProt Code:Q9UM01
NCBI GenInfo Identifier:186910306
NCBI Gene ID:9056
NCBI Accession:NP_001119577.1
UniProt Related Accession:Q9UM01
Molecular Weight:
NCBI Full Name:Y+L amino acid transporter 1
NCBI Synonym Full Names:solute carrier family 7 member 7
NCBI Official Symbol:SLC7A7  
NCBI Official Synonym Symbols:LPI; LAT3; MOP-2; Y+LAT1; y+LAT-1  
NCBI Protein Information:Y+L amino acid transporter 1
UniProt Protein Name:Y+L amino acid transporter 1
UniProt Synonym Protein Names:Monocyte amino acid permease 2; MOP-2; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1
Protein Family:Y+L amino acid transporter
UniProt Gene Name:SLC7A7  

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