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Anti-ST7 Antibody (CAB14384)

SKU:
CAB14384
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€129 - €359
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Description

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Antibody Name:Anti-ST7 Antibody
Antibody SKU:CAB14384
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 200-290 of human ST7 (NP_068708.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 200-290 of human ST7 (NP_068708.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QARI SAAH EALE INEI RSRV EVPL IASS TIWE IKLL PKCA TAYI LLAE EEAT TIAE AEKL FKQA LKAG DGCY RRSQ QLQH HGSQ YEAQ HRR
Gene ID:7982
Uniprot:Q9NRC1
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:45kDa/56kDa/58kDa/60kDa/62kDa/63kDa/67kDa
Observed MW:Refer to Figures
Synonyms:ST7, ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7
Background:The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described.
UniProt Protein Function:ST7: May act as a tumor suppressor. Belongs to the ST7 family. 7 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 7q31.2

Cellular Component: integral to membrane

NCBI Summary:The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NRC1
NCBI GenInfo Identifier:74734319
NCBI Gene ID:7982
NCBI Accession:Q9NRC1.1
UniProt Related Accession:Q9NRC1
Molecular Weight:43kDa
NCBI Full Name:Suppressor of tumorigenicity 7 protein
NCBI Synonym Full Names:suppression of tumorigenicity 7
NCBI Official Symbol:ST7  
NCBI Official Synonym Symbols:HELG; RAY1; SEN4; TSG7; ETS7q; FAM4A; FAM4A1  
NCBI Protein Information:suppressor of tumorigenicity 7 protein
UniProt Protein Name:Suppressor of tumorigenicity 7 protein
UniProt Synonym Protein Names:Protein FAM4A1; Protein HELG
Protein Family:Suppressor of tumorigenicity 7 protein
UniProt Gene Name:ST7  
UniProt Entry Name:ST7_HUMAN

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