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Description
Overview:
Title: | AF/LE Purified Anti-Mouse CD3 Antibody [17A2] |
Synonyms: | T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain,CD3E/D/G/Z,CD3e/d/g/z,CD3E/D/G/Z,CD3 |
Uniprot: | P04235 , P11942, P22646, P24161 |
Size: | 500µg |
Reactivity: | Mouse |
Application: | FCM |
Host: | Rat |
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Product Information:
Isotype: | Rat IgG2b, κ |
Form: | Liquid |
Storage: | Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Buffer: | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Conjugation: | None (Purified antibody/Azide Free/Low endotoxin) |