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CD68 Monoclonal Antibody

SKU:
AGEL2125
Product type:
Antibody
Application:
FC
€299
Frequently bought together:

Description

Overview:
Title: CD68 Monoclonal Antibody
Reactivity: Human
Application: IHC, IF
Dilution: IHC 1:100-1:300, IF 1:50 - 1:200
Host Mouse

Background:

CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.

Product Information:
Clonality: Monoclonal
Isotype: IgG
Concentration: 1 mg/mL
Storage: Store at -20„ƒ. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method: Protein A purification
Research Areas: Cancer, Immunology
Clone No: 2K6
Conjugation: Unconjugated
Immunogen Details:
Immunogen: Synthetic Peptide
Abbre: CD68
Synonyms: CD 68,CD68,CD68 antigen,CD68 molecule,CD68,DKFZp686M18236,gp11,Gp110,LAMP4,Macrophage antigen CD68 (microsialin),MACROPHAGE ANTIGEN CD68,Macrosialin,SCARD1,Scavenger receptor class D member 1.
Swissprot: P34810
Cellular Localization: Membrane.
Tissue Specificity: Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.