The GPR64 Polyclonal Antibody (PAC018019) is a valuable tool for researchers studying GPR64, a G protein-coupled receptor involved in various cellular processes and signaling pathways. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it suitable for a range of applications including Western blot analysis. By targeting the GPR64 protein, this antibody allows for the detection and examination of GPR64 expression in different cell types, making it an ideal choice for studies in cell biology and drug discovery.
GPR64, also known as the ovarian cancer G-protein coupled receptor 1, is implicated in a variety of physiological functions, including cell proliferation, migration, and hormone signaling. Its role in these processes makes GPR64 a potential target for research in cancer biology, reproductive health, and metabolic disorders. By understanding the function and regulation of GPR64, researchers can gain valuable insights into disease mechanisms and develop novel therapeutic strategies targeting this receptor.
Antibody Name:
GPR64 Antibody (PACO18019)
Antibody SKU:
PACO18019
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human GPR64
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18019(GPR64 Antibody) at dilution 1/55, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms:
G protein-coupled receptor 64
UniProt Protein Function:
GPR64: Could be involved in a signal transduction pathway controlling epididymal function and male fertility. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 9 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Receptor, GPCRChromosomal Location of Human Ortholog: Xp22.13Cellular Component: cell surface; integral to plasma membrane; apical plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; spermatogenesis
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
G-protein coupled receptor 64; epididymal protein 6; human epididymis-specific protein 6; G protein-coupled receptor, epididymis-specific (seven transmembrane family)
