The OR4E2 Polyclonal Antibody (PACO03854) is a valuable tool for researchers studying OR4E2, a member of the olfactory receptor family involved in the detection of odorants. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used in immunohistochemistry and Western blotting procedures.OR4E2, also known as Olfactory Receptor Family 4 Subfamily E Member 2, is expressed in olfactory sensory neurons and plays a key role in the perception of odors.
Research into OR4E2 can provide insights into the mechanisms of olfaction and contribute to the development of novel therapies for smell-related disorders.By utilizing the OR4E2 Polyclonal Antibody (PACO03854), researchers can effectively detect and analyze OR4E2 protein expression in various tissues and cell types, advancing our understanding of the olfactory system and its functional significance in human health and disease.
Antibody Name:
OR4E2 Antibody
Antibody SKU:
PACO03854
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4E2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4E2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-passChromosomal Location of Human Ortholog: 14q11.2Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activity; transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; detection of chemical stimulus involved in sensory perception of smell; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
