PIP5KL1 Antibody (PACO11258)
- SKU:
- PACO11258
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
PIP5KL1 Antibody (PACO11258)
The PIP5KL1 Antibody (PAC011258) is a valuable tool for researchers studying the PIP5KL1 protein, which is involved in lipid metabolism and intracellular signaling pathways. This polyclonal antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting PIP5KL1 in human samples, making it an ideal choice for Western blot applications. By targeting the PIP5KL1 protein, this antibody enables researchers to investigate the function and regulation of PIP5KL1 in various cellular processes, with potential applications in the fields of cell biology and lipid signaling research.PIP5KL1 is a key player in lipid metabolism, particularly in the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2), a crucial signaling molecule involved in cell proliferation, cytoskeletal dynamics, and membrane trafficking.
Dysregulation of PIP5KL1 has been implicated in various diseases, including cancer and neurological disorders, highlighting the importance of studying its role in cellular function. By using the PIP5KL1 Antibody, researchers can gain insights into the molecular mechanisms underlying these pathologies, potentially leading to the development of novel therapeutic strategies targeting PIP5KL1-mediated pathways.
| Antibody Name: | PIP5KL1 Antibody (PACO11258) |
| Antibody SKU: | PACO11258 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PIP5KL1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | phosphatidylinositol-4-phosphate 5-kinase-like 1;PIP5KL1;MGC46424;PIPKH;bA203J24.5 ; |
| UniProt Protein Function: | PIP5KL1: May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Kinase, lipid; EC 2.7.1.68 Chromosomal Location of Human Ortholog: 9q34.11 Cellular Component: cell projection; membrane; cytoplasm Molecular Function:1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding Biological Process: phosphoinositide phosphorylation |
| NCBI Summary: | PIP5KL1 is a phosphoinositide kinase-like protein that lacks intrinsic lipid kinase activity but associates with type I PIPKs (see PIP5K1A; MIM 603275) and may play a role in localization of PIPK activity (Chang et al., 2004 [PubMed 14701839]).[supplied by OMIM, Jun 2009] |
| UniProt Code: | Q5T9C9 |
| NCBI GenInfo Identifier: | 146325056 |
| NCBI Gene ID: | 138429 |
| NCBI Accession: | Q5T9C9.2 |
| UniProt Related Accession: | Q5T9C9 |
| Molecular Weight: | |
| NCBI Full Name: | Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 |
| NCBI Synonym Full Names: | phosphatidylinositol-4-phosphate 5-kinase like 1 |
| NCBI Official Symbol: | PIP5KL1 |
| NCBI Official Synonym Symbols: | PIPKH |
| NCBI Protein Information: | phosphatidylinositol 4-phosphate 5-kinase-like protein 1 |
| UniProt Protein Name: | Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 |
| UniProt Gene Name: | PIP5KL1 |
| UniProt Entry Name: | PI5L1_HUMAN |
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