The RHCE Polyclonal Antibody (PAC020338) is a valuable tool for researchers studying the RHCE antigen, a blood group antigen found on red blood cells. This antibody, produced in rabbits, is highly specific and reacts strongly with human samples, making it suitable for use in various research applications such as Western blotting.The RHCE antigen is an important marker in blood group typing and compatibility testing for blood transfusions and organ transplants. The RHCE Polyclonal Antibody can accurately detect the presence of the RHCE antigen, aiding in the identification and characterization of different blood types.
Researchers in the fields of hematology, transfusion medicine, and immunology can benefit from using the RHCE Polyclonal Antibody to study the RHCE antigen's expression patterns and functions. This antibody enables precise detection and analysis of the RHCE antigen, facilitating research into blood group genetics, transfusion reactions, and other related areas of study.
Antibody Name:
RHCE Antibody (PACO20338)
Antibody SKU:
PACO20338
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human RHCE
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE,Lysate: 40 µg,Lane 1-2: 231 cells, Human breast infiltrative duct tissue,Primary antibody: PACO20338(RHCE Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute.
Background:
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes.
Synonyms:
Rh blood group, CcEe antigens
UniProt Protein Function:
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
UniProt Protein Details:
NCBI Summary:
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Aug 2016]
