The TCEAL1 Polyclonal Antibody (PAC022653) is a valuable tool for researchers studying the TCEAL1 gene, which plays a role in transcriptional regulation and cell proliferation. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. It binds to the TCEAL1 protein, allowing for accurate detection and analysis in a variety of cell types, making it well-suited for investigations in molecular biology and cancer research.TCEAL1, also known as Transcription Elongation Factor A Like 1, is involved in the regulation of gene expression and cell growth, making it an important target for studies on cancer and other diseases related to aberrant gene regulation.
By elucidating the function of TCEAL1, researchers can gain insights into the mechanisms underlying disease development and potentially identify novel therapeutic targets for intervention. This antibody provides researchers with a valuable tool to investigate the role of TCEAL1 in various biological processes.
Antibody Name:
TCEAL1 Antibody (PACO22653)
Antibody SKU:
PACO22653
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human TCEAL1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from COLO cells, using TCEAL1 antibody.
Background:
May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.
May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
