The TEX10 Polyclonal Antibody (PACO12701) is an essential tool for researchers studying TEX10, a critical protein involved in transcription and RNA processing. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards TEX10 in human samples, making it suitable for use in Western blotting and immunohistochemistry experiments. By targeting the TEX10 protein, this antibody enables accurate detection and analysis of TEX10 expression in various cell types, offering valuable insights for studies in molecular biology and gene regulation.TEX10, also known as Testis Expressed 10, is a key player in the regulation of gene expression, particularly in the context of spermatogenesis and embryonic development.
Its role in RNA processing and transcriptional control highlights its significance in various biological processes, making it a promising target for research in reproductive biology and developmental genetics. Investigating the functions of TEX10 is crucial for unraveling its contributions to normal physiology and disease pathology, paving the way for potential therapeutic interventions in reproductive disorders and developmental abnormalities.
Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211).
