The TGM7 Polyclonal Antibody (PAC020751) is a valuable tool for researchers studying transglutaminase 7 (TGM7), an enzyme involved in various biological processes such as cell proliferation and differentiation. This antibody, produced in rabbits, is highly specific for human samples and is suitable for use in Western blot and immunohistochemistry applications. By targeting the TGM7 protein, this antibody allows for the detection and analysis of TGM7 expression in different cell types, making it ideal for studies in cell biology and disease pathology.TGM7 is known for its role in the regulation of cell growth and differentiation, making it a potential target for research into diseases like cancer and neurodegenerative disorders.
The ability to study TGM7 expression and function using this antibody can provide valuable insights into the molecular mechanisms underlying these conditions, ultimately leading to the development of novel therapeutic strategies. Researchers interested in investigating the role of TGM7 in various biological processes will find this antibody to be an essential tool in their studies.
Antibody Name:
TGM7 Antibody (PACO20751)
Antibody SKU:
PACO20751
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human TGM7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 6%SDS-PAGE, Lysate: 40 µg, Lane: Mouse eyes tissue, Primary antibody: PACO20751(TGM7 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds.
Background:
Transglutaminases (TGM; EC 2.3.2.13) are a family of structurally and functionally related enzymes that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. For additional background information on transglutaminases, see TGM1 (MIM 190195).
Synonyms:
transglutaminase 7
UniProt Protein Function:
TGM7: an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Protein type: EC 2.3.2.13; TransferaseChromosomal Location of Human Ortholog: 15q15.2
