The ZADH2 Polyclonal Antibody (PACO22702) is a valuable tool for researchers studying the ZADH2 protein, which plays a key role in cellular metabolism and energy production. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ZADH2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in metabolism, bioenergetics, and cancer research.ZADH2, also known as zinc-binding alcohol dehydrogenase domain-containing protein 2, is involved in the regulation of cellular processes related to energy metabolism and mitochondrial function.
Its dysregulation has been associated with metabolic disorders and cancer progression, making it a promising target for therapeutic interventions. Research into the function and regulation of ZADH2 is essential for developing new treatments for metabolic diseases and cancer.Overall, the ZADH2 Polyclonal Antibody (PACO22702) is a reliable tool for studying the role of ZADH2 in cellular metabolism and its implications in disease, providing valuable insights for future research and therapeutic development.
Antibody Name:
ZADH2 Antibody (PACO22702)
Antibody SKU:
PACO22702
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human ZADH2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from COLO cells, HUVEC cells and HT-29 cells, using ZADH2 antibody.
Background:
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficienty towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
