The BLOC1S3 Polyclonal Antibody (CAB17281) is a vital tool for researchers studying BLOC1S3, a key protein involved in cellular transport and organelle biogenesis. Raised in rabbits, this antibody offers high reactivity with human samples and has been validated for use in Western blot applications. By targeting the BLOC1S3 protein, researchers can accurately detect and analyze its expression in various cell types, making it an ideal choice for studies in cell biology and molecular biology.
BLOC1S3 is a subunit of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), which is essential for normal organelle function and membrane trafficking. Dysregulation of BLOC1S3 has been linked to various diseases, including neurodegenerative disorders and metabolic conditions. By gaining insights into the function of BLOC1S3, researchers can uncover potential therapeutic targets for these diseases and develop novel treatment strategies.
Product Name:
BLOC1S3 Rabbit Polyclonal Antibody
SKU:
CAB17281
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human BLOC1S3 (NP_997715.1).
This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.
Purification Method:
Affinity purification
Gene ID:
388552
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human colon using BLOC1S3 Rabbit pAb (CAB17281) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
