Human Hepatitis B Virus x Interacting Protein Recombinant Protein (CPRT5508)

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CPRT5508
€278

Description

Data SheetMSDS

HBXIP Human Recombinant Protein

Name:HBXIP Human
Synonyms:Ragulator complex protein LAMTOR5, Hepatitis B virus X-interactingprotein, HBV X-interactingprotein, HBX-interactingprotein, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5, LAMTOR5, HBXIP, XIP.
Introduction:Hepatitis B virus x interactingprotein (HBXIP) forms a complex with the C–terminus of hepatitis B virus X (HBX) protein. HBXIP negatively regulates HBX activity and changes the replicative life cycle of the virus. Furthermore, HBXIP is involved in bipolar spindle formation and regulates centrosome dynamics and cytokinesis in cells, possibly due to interaction with Dynein light chain. HBXIP is highly expressed in the skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. HBXIP has elevated levels in both cancerous and non–cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.
Description:HBXIP Human Recombinant produced in E. coli is a single polypeptide chain containing 197 amino acids (aa 1–173) and having a molecular mass of 20.7kDa.HBXIP is fused to a 24 amino acid His–tag at N–terminus & purified by proprietary chromatographic techniques.
Source:Escherichia Coli.
Pack size:20µg
Physical Appearance:Sterile filtered colorless solution.
Formulation:The HBXIP solution (1mg/ml) contains 20mM Tris–HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM EDTA.
Solubility:N/A
Stability:Store at 4°C if entire vial will be used within 2–4 weeks. Store, frozen at –20°C for longer periods of time. For longterm storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze–thaw cycles.
Purity:Greater than 90% as determined by SDS–PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMEPGAgHLDGHRAGSP SLRQALCDGS AVMFSSKERgRCTVINFVPL EAPLRSTPRS RQVTEACGGE GRAVPLGSEP EWSVGGMEAT LEQHLEDTMK NPSIVGVLCT DSQGLNLGCR GTLSDEHAGV ISVLAQQAAK LTSDPTDIPV VCLESDNGNI MIQKHDGITV AVHKMAS.
Biological Activity:N/A
Usage:Assay Genie’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Uniprot:O43504
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Additional Information

Product type:
Recombinant Protein
Reactivity:
Human
Host Species:
E.Coli
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