null

Human PD-L1 Recombinant Protein (His Tag) (HDPT0092)

SKU:
HDPT0092
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint
€562
Frequently bought together:

Description

Human PD-L1 Recombinant Protein (His Tag)

Description:This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
Product name:Human PD-L1 Recombinant Protein (His Tag)
Synonyms:PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
Type:protein
Size:50 µg
Name:PD-L1
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:PD-L1(Phe19-Arg328)+6×His tag
Gene ID:29126
Uniprot:Q9NZQ7
Molecular Weight:26.0 kDa