MCAT Antibody (PACO54142)
- SKU:
- PACO54142
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MCAT Antibody (PACO54142) |
Antibody SKU: | PACO54142 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Recombinant Human Malonyl-CoA-acyl carrier protein transacylase, mitochondrial protein (22-117AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Rat heart tissue, Mouse liver tissue. All lanes: MCAT antibody at 2.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 43, 20 kDa. Observed band size: 43 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO54142 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human liver tissue using PACO54142 at dilution of 1:100. |
Background: | Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acid, in mitochondrias. |
Synonyms: | Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyl CoA:ACP acyltransferase) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase), MCAT, MT |
UniProt Protein Function: | MCAT: Catalyzes the transfer of a malonyl moiety from malonyl- CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondrias. Belongs to the type II malonyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Lipid Metabolism - fatty acid biosynthesis; EC 2.3.1.39; Transferase Chromosomal Location of Human Ortholog: 22q13.31 Cellular Component: mitochondrion Molecular Function:[acyl-carrier-protein] S-malonyltransferase activity; transferase activity Biological Process: fatty acid biosynthetic process; metabolic process |
NCBI Summary: | The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012] |
UniProt Code: | Q8IVS2 |
NCBI GenInfo Identifier: | 48428076 |
NCBI Gene ID: | 27349 |
NCBI Accession: | Q8IVS2.2 |
UniProt Secondary Accession: | Q8IVS2,O95510, O95511, B0QY72, |
UniProt Related Accession: | Q8IVS2 |
Molecular Weight: | 19,176 Da |
NCBI Full Name: | Malonyl-CoA-acyl carrier protein transacylase, mitochondrial |
NCBI Synonym Full Names: | malonyl-CoA-acyl carrier protein transacylase |
NCBI Official Symbol: | MCAT |
NCBI Official Synonym Symbols: | MT; MCT; fabD; NET62; FASN2C |
NCBI Protein Information: | malonyl-CoA-acyl carrier protein transacylase, mitochondrial |
UniProt Protein Name: | Malonyl-CoA-acyl carrier protein transacylase, mitochondrial |
UniProt Synonym Protein Names: | Mitochondrial malonyl CoA:ACP acyltransferase; Mitochondrial malonyltransferase; [Acyl-carrier-protein] malonyltransferase |
Protein Family: | Malonyl-CoA-acyl carrier protein transacylase |
UniProt Gene Name: | MCAT |
UniProt Entry Name: | FABD_HUMAN |
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Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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