Anti-MCAT Antibody (PACO54142)

Antibody Name:	MCAT Antibody (PACO54142)
Antibody SKU:	PACO54142
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant Human Malonyl-CoA-acyl carrier protein transacylase, mitochondrial protein (22-117AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western Blot. Positive WB detected in: Rat heart tissue, Mouse liver tissue. All lanes: MCAT antibody at 2.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 43, 20 kDa. Observed band size: 43 kDa.
	Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO54142 at dilution of 1:100.
	Immunohistochemistry of paraffin-embedded human liver tissue using PACO54142 at dilution of 1:100.

Background:	Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acid, in mitochondrias.
Synonyms:	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyl CoA:ACP acyltransferase) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase), MCAT, MT

UniProt Protein Function:	MCAT: Catalyzes the transfer of a malonyl moiety from malonyl- CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondrias. Belongs to the type II malonyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Lipid Metabolism - fatty acid biosynthesis; EC 2.3.1.39; Transferase Chromosomal Location of Human Ortholog: 22q13.31 Cellular Component: mitochondrion Molecular Function:[acyl-carrier-protein] S-malonyltransferase activity; transferase activity Biological Process: fatty acid biosynthetic process; metabolic process
NCBI Summary:	The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012]
UniProt Code:	Q8IVS2
NCBI GenInfo Identifier:	48428076
NCBI Gene ID:	27349
NCBI Accession:	Q8IVS2.2
UniProt Secondary Accession:	Q8IVS2,O95510, O95511, B0QY72,
UniProt Related Accession:	Q8IVS2
Molecular Weight:	19,176 Da
NCBI Full Name:	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
NCBI Synonym Full Names:	malonyl-CoA-acyl carrier protein transacylase
NCBI Official Symbol:	MCAT
NCBI Official Synonym Symbols:	MT; MCT; fabD; NET62; FASN2C
NCBI Protein Information:	malonyl-CoA-acyl carrier protein transacylase, mitochondrial
UniProt Protein Name:	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
UniProt Synonym Protein Names:	Mitochondrial malonyl CoA:ACP acyltransferase; Mitochondrial malonyltransferase; [Acyl-carrier-protein] malonyltransferase
Protein Family:	Malonyl-CoA-acyl carrier protein transacylase
UniProt Gene Name:	MCAT
UniProt Entry Name:	FABD_HUMAN

Antibodies	ELISA Kits
Anti-MCAT Antibody (CAB15822)	Human Melatonin ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)