The MOB3B Polyclonal Antibody (PAC021887) is a valuable tool for researchers studying MOB3B, a key protein involved in various cellular processes such as cell division and growth. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By targeting the MOB3B protein, this antibody allows for the detection and analysis of MOB3B expression in different cell types, making it ideal for research in cell biology and cancer studies.MOB3B is a crucial component in the regulation of cell cycle progression and proliferation, making it a potential target for investigating diseases like cancer where abnormal cell growth occurs.
By understanding the function of MOB3B, researchers can gain insights into the mechanisms underlying these diseases and potentially uncover new therapeutic strategies. The MOB3B Polyclonal Antibody offers researchers a reliable tool for exploring the role of MOB3B in various cellular processes and disease contexts.
Antibody Name:
MOB3B Antibody (PACO21887)
Antibody SKU:
PACO21887
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human MOL2B.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen The MGC Project Team, Genome Res. 14:2121-2127(2004).
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Western blot analysis of extracts from COLO cells, using MOL2B antibody.
Synonyms:
Mps one binder kinase activator-like 2B; Mob1 homolog 2b; Protein Mob3B; MOBKL2B; MOB3B
UniProt Protein Function:
MOBKL2B: May regulate the activity of kinases. Belongs to the MOB1/phocein family.
UniProt Protein Details:
Chromosomal Location of Human Ortholog: 9p21.2
Molecular Function:protein binding
NCBI Summary:
The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008]
