The MRCA Antibody (PAC049154) is a highly specific and sensitive tool for researchers studying the MRCA protein, which plays a crucial role in cell signaling and immune response regulation. This polyclonal antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for Western blot applications.The MRCA protein, also known as a key modulator of immune responses, is involved in regulating the activation and function of immune cells. Studies have shown that dysregulation of MRCA expression can lead to aberrant immune responses, making it a potential target for therapeutic interventions in diseases such as cancer, autoimmune disorders, and inflammatory conditions.
By using the MRCA Antibody, researchers can detect and analyze MRCA protein levels in various cell types, shedding light on its role in immune modulation and disease pathogenesis. This antibody is an indispensable tool for investigations in immunology, cancer biology, and drug development, providing valuable insights into the intricate mechanisms of immune regulation.
Antibody Name:
mrcA Antibody (PACO49154)
Antibody SKU:
PACO49154
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli Penicillin-binding protein 1A protein (229-529AA)
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
UniProt Protein Details:
NCBI Summary:
The N-terminal transglycosylase activity polymerizes the glycan backbone and is penicillin-insensitive. [More information is available at EcoGene: EG10748]. PBP1A, the product of the mrcA gene, is a bifunctional, inner membrane enzyme catalyzing the transglycosylation and transpeptidation of murein (peptidoglycan) precursors in the formation of the murein sacculus. [More information is available at EcoCyc: EG10748].
