The RGL2 Polyclonal Antibody (CAB22119) is a valuable tool for researchers studying RGL2, a protein involved in various cellular processes, including cell signaling and differentiation. This antibody, raised in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications.RGL2, also known as Ral guanine nucleotide dissociation stimulator-like 2, plays a crucial role in regulating cell growth and survival. Its involvement in signaling pathways makes it an important target for research in cancer biology and developmental biology. By binding to the RGL2 protein, this antibody allows for the detection and analysis of RGL2 expression in different cell types, providing valuable insights into its functions.
Understanding the functions of RGL2 is essential for unraveling its contribution to various biological processes and diseases. Research on RGL2 can provide insights into cancer development, neuronal signaling, and cell proliferation, offering potential avenues for therapeutic interventions. The RGL2 Polyclonal Antibody is a valuable tool for researchers investigating the role of RGL2 in health and disease.
Product Name:
RGL2 Polyclonal Antibody
SKU:
CAB22119
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Arabidopsis thaliana
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-156 of arabidopsis thaliana RGL2 (NP_186995.1).
Encodes a DELLA protein, a member of the GRAS superfamily of putative transcription factors. DELLA proteins restrain the cell proliferation and expansion that drives plant growth. Negative regulator of the response to GA in controlling seed germination. GA triggers the degradation of RGL2 protein in a process blocked by both proteasome inhibitors and serine/threonine phosphatase inhibitors. The protein undergoes degradation in response to GA via the 26S proteasome. RGL2 may be involved in reducing ROS accumulation in response to stress by up-regulating the transcription of superoxide dismutases. Rapidly degraded in response to GA. Regulates GA-promoted seed germination. Involved in flower and fruit development.
Purification Method:
Affinity purification
Gene ID:
821251
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various tissues from Arabidopsis thaliana, using RGL2 Rabbit pAb (CAB22119) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
