The SCAF1 Polyclonal Antibody (PACO01473) is a valuable tool for researchers studying SCAF1, a protein involved in RNA processing and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the SCAF1 protein, this antibody enables the detection and analysis of SCAF1 in a variety of cell types, making it an essential component for studies in molecular biology and RNA processing mechanisms.SCAF1, also known as SR-related CTD-associated factor 1, is a key player in RNA metabolism and influences various cellular processes such as mRNA splicing and transcriptional regulation.
By investigating the function and expression of SCAF1, researchers can gain insights into its role in gene expression and potential implications in diseases such as cancer and neurological disorders. The SCAF1 Polyclonal Antibody is a valuable tool for dissecting the molecular mechanisms involving SCAF1 and exploring its therapeutic potential in various conditions.
Antibody Name:
SCAF1 Antibody
Antibody SKU:
PACO01473
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the N-terminal region of human SCAF1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function: May function in pre-mRNA splicing By similarity.Subunit structure: Interacts with POLR2A. Ref.5Subcellular location: Nucleus Probable. Tissue specificity: Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa. Ref.1 Ref.4 Ref.6 Ref.7Induction: Up-regulated by estrogens, androgens and glucocorticoids. Ref.1Sequence similarities: Belongs to the splicing factor SR family.Sequence caution: The sequence BAB15734.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
