The SerpinB10 Polyclonal Antibody (PACO12110) is a valuable tool for researchers studying SerpinB10, a serine protease inhibitor involved in regulating inflammatory responses. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the SerpinB10 protein, researchers can detect and analyze its expression in various cell types, making it an ideal choice for studies in immunology and cancer research.SerpinB10 is known to play a role in modulating immune responses and controlling inflammation, making it a key player in the development of therapies for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of SerpinB10 is essential for unlocking its potential as a therapeutic target in these disease contexts.Overall, the SerpinB10 Polyclonal Antibody (PACO12110) is a versatile tool for researchers looking to dive deeper into the role of SerpinB10 in immune regulation and its implications for disease pathology.
serpin peptidase inhibitor, clade B (ovalbumin), member 10;SERPINB10;PI10;bomapin ;
UniProt Protein Function:
SERPINB10: Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. Belongs to the serpin family. Ov-serpin subfamily.Protein type: InhibitorChromosomal Location of Human Ortholog: 18q21.3Cellular Component: extracellular space; cytoplasm; nucleusMolecular Function: serine-type endopeptidase inhibitor activity
UniProt Protein Details:
NCBI Summary:
This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate cancer. [provided by RefSeq, Dec 2015]