The SMAP2 Polyclonal Antibody (PAC012328) is a valuable tool for researchers studying SMAP2, a protein involved in intracellular membrane trafficking and cell signaling. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications.SMAP2 functions as a guanine nucleotide exchange factor for small GTPases, playing a key role in the regulation of endocytic trafficking and vesicle formation within cells. Its role in cellular processes makes it an intriguing target for research in the fields of cell biology and molecular biology.
The SMAP2 Polyclonal Antibody enables the detection and analysis of SMAP2 protein levels in various cell types, providing valuable insights into its function and potential implications in disease. Studies utilizing this antibody may lead to a better understanding of intracellular trafficking mechanisms and could offer new opportunities for therapeutic interventions in diseases related to aberrant vesicle trafficking.
SMAP1L: GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network. 3 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, ARF; GAPsChromosomal Location of Human Ortholog: 1p35.3-p34.1Cellular Component: cytoplasm; nucleoplasmMolecular Function: protein binding
