The TAS2R16 Polyclonal Antibody (PACO4506) is a valuable tool for researchers studying TAS2R16, a bitter taste receptor protein known for its role in taste perception and potentially in other physiological processes as well. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards TAS2R16 in human samples, making it an excellent choice for Western blotting and immunohistochemistry applications.TAS2R16 is part of the TAS2R family of receptors, which play a crucial role in sensing bitter compounds in the diet and initiating appropriate physiological responses. Recent studies have suggested that TAS2R16 may also be involved in other functions such as regulating glucose homeostasis and lipid metabolism.
The ability to accurately detect and analyze TAS2R16 using this antibody provides researchers with a powerful tool for investigating the role of bitter taste receptors in various biological processes.By studying TAS2R16 and its interactions with bitter compounds and potential ligands, researchers can gain insights into the molecular mechanisms underlying taste perception and its implications for health and disease. The TAS2R16 Polyclonal Antibody (PACO4506) is an essential resource for unravelling the functions of this intriguing taste receptor and its potential therapeutic applications in the fields of nutrition, sensory biology, and metabolic disorders.
Antibody Name:
TAS2R16 Antibody
Antibody SKU:
PACO04506
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human T2R16.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TAS2R16; Taste receptor type 2 member 16; T2R16
UniProt Protein Function:
TAS2R16: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, T2R familyChromosomal Location of Human Ortholog: 7q31.1-q31.3|7q31Cellular Component: endoplasmic reticulum; plasma membrane; integral to membrane; trans-Golgi network; external side of plasma membraneMolecular Function: bitter taste receptor activity; protein bindingBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of bitter tasteDisease: Alcohol Dependence
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]
