The UBXN4 Polyclonal Antibody (PAC013061) is a valuable tool for researchers studying UBXN4, a protein involved in cellular processes such as protein degradation and DNA repair. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting UBXN4 in human samples, making it ideal for use in Western blot applications. By targeting the UBXN4 protein, researchers can gain insights into its function in various cell types, particularly in the context of cancer biology and DNA damage response pathways.
UBXN4 is known to play a critical role in protein quality control and cellular stress response mechanisms, making it a promising target for understanding disease mechanisms and developing targeted therapies. By studying UBXN4 with the PAC013061 antibody, researchers can uncover new insights into its role in disease progression and potentially identify novel therapeutic strategies for conditions such as cancer and neurodegenerative disorders.
UBX domain protein 4;UBXN4;FLJ23318;KIAA0242;KIAA2042;UBXD2;UBXDC1;erasin ;
UniProt Protein Function:
UBXN4: Involved in endoplasmic reticulum-associated protein degradation (ERAD).Protein type: Chaperone; Endoplasmic reticulum; Ubiquitin conjugating system; Membrane protein, integralChromosomal Location of Human Ortholog: 2q21.3Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; cytoplasm; nuclear envelopeMolecular Function: protein bindingBiological Process: response to unfolded protein
UniProt Protein Details:
NCBI Summary:
UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP; MIM 601023) and promotes ER-associated protein degradation (ERAD) (Liang et al., 2006 [PubMed 16968747]).[supplied by OMIM, Mar 2008]
