The UGT3A1 Polyclonal Antibody (PAC013083) is a valuable tool for research focusing on UGT3A1, a member of the UDP-glucuronosyltransferase enzyme family involved in drug metabolism and detoxification processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it an excellent choice for Western blot applications.UGT3A1 plays a crucial role in the conjugation of endogenous compounds and xenobiotics, enhancing their solubility for excretion from the body. Its expression levels and activity have been linked to drug efficacy and toxicity, making it a target of interest in pharmacology and toxicology studies.
With this antibody, researchers can accurately detect and quantify UGT3A1 protein levels in different cell types, aiding in the investigation of drug metabolism pathways and the development of personalized medicine approaches.Overall, the UGT3A1 Polyclonal Antibody is an essential tool for scientists studying drug metabolism, toxicology, and personalized medicine, offering reliable and accurate detection of UGT3A1 protein levels in various research applications.
UGT3A1: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family.Protein type: Membrane protein, integral; EC 2.4.1.17; TransferaseChromosomal Location of Human Ortholog: 5p13.2Cellular Component: integral to membraneMolecular Function: glucuronosyltransferase activity; UDP-glycosyltransferase activityBiological Process: flavonoid biosynthetic process; cellular response to hormone stimulus
