The uPAR (U-Par) Monoclonal Antibody is a cutting-edge tool for researchers studying uPAR, a protein receptor involved in cell adhesion, migration, and invasion processes. This monoclonal antibody is highly specific to human samples and is optimized for use in various applications, including immunofluorescence, immunohistochemistry, and flow cytometry.The uPAR protein is known for its role in cancer metastasis and progression, making it a key target for studies in oncology and cancer biology. By targeting uPAR with this monoclonal antibody, researchers can gain valuable insights into the mechanisms underlying tumor growth and spread, potentially leading to the development of novel anti-cancer therapies.
With its high specificity and versatility, the uPAR Monoclonal Antibody is an essential tool for researchers looking to deepen their understanding of uPAR biology and its implications in cancer research. Harness the power of this innovative antibody to unlock new discoveries in the field of oncology and beyond.
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Purification Method:
Affinity purification
Gene ID:
5329
Clone Number:
ARC60627
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunofluorescence analysis of U-87MG cells using uPAR/U-PAR Rabbit mAb (CAB23293) at dilution of 1:300 (40x lens). Blue: DAPI for nuclear staining.
