The ATF7IP Polyclonal Antibody (CAB10446) is a valuable tool for researchers studying ATF7IP, a transcription factor involved in gene regulation and cell proliferation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to ATF7IP, the antibody enables accurate detection and analysis in a variety of cell types, making it an essential component in studies relating to gene expression and cell growth.
ATF7IP is known to play a crucial role in various cellular processes, including DNA damage response and cell cycle regulation. Its involvement in gene transcription and cell proliferation makes it a promising target for research in cancer biology and developmental biology. By understanding the functions of ATF7IP, researchers can gain insights into mechanisms underlying diseases such as cancer and potentially identify new therapeutic strategies targeting ATF7IP-mediated pathways.
Product Name:
ATF7IP Rabbit Polyclonal Antibody
SKU:
CAB10446
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 525-725 of human ATF7IP (NP_060649.3).
ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).
Purification Method:
Affinity purification
Gene ID:
55729
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ATF7IP antibody (CAB10446) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
