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Human TGFB1 Recombinant Protein (hFc Tag) (HDPT0164)

SKU:
HDPT0164
Product Type:
Recombinant Protein
Host Species:
HEK293
Reactivity:
Human
€630
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Description

Human TGFB1 Recombinant Protein (hFc Tag)

Description:This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Product name:Human TGFB1 Recombinant Protein (hFc Tag)
Synonyms:CED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta
Type:protein
Size:50 µg
Name:TGFB1
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 90%
Purification:affinity purification
Format:Lyophilized
Conjugate:N-Human Fc tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:hFc(Glu99-Ala330)+TGFB1(Ala279-Ser359)
Gene ID:7040
Uniprot:P01137
Molecular Weight:38.9 kDa