The PRPF40B Polyclonal Antibody (PAC011499) is a valuable tool for researchers studying PRPF40B, a key component of the spliceosome complex involved in RNA splicing. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PRPF40B protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential reagent for studies in molecular biology and gene expression regulation.
PRPF40B plays a crucial role in pre-mRNA splicing, a fundamental process in gene expression that is dysregulated in many diseases, including cancer and genetic disorders. Understanding the function and regulation of PRPF40B is essential for unraveling the complexities of gene expression and identifying potential therapeutic targets for various diseases. The PRPF40B Polyclonal Antibody is a valuable tool for researchers seeking to elucidate the role of PRPF40B in RNA splicing and its implications for human health.
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae);PRPF40B;HYPC ;
UniProt Protein Function:
May be involved in pre-mRNA splicing.
UniProt Protein Details:
NCBI Summary:
This gene encodes a WW-domain containing protein similar to yeast splicing factor PRP40. This protein has been shown to interact with Huntingtin and methyl CpG binding protein 2 (MeCP2). Alternative splicing results in different transcript variants. [provided by RefSeq, Aug 2014]
