Mouse Kallikrein 7/KLK7 Recombinant Protein (RPES4873)

SKU:
RPES4873
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Mouse
€196

Description

ELISA Kit Technical Manual

Recombinant Mouse Kallikrein 7/KLK7 Protein (His Tag)

Background:Kallikrein7, also named as stratum corneum chymotryptic enzyme (SCCE), is a secreted protein of the Kallikrein-related peptidase (KLK) family. This family contains fifteen homologous secreted serine endopeptidases and plays a significant role in various physiological processes, including skin desquamation, semen liquefaction, neural plasticity, and body fluid homeostasis. In skin KLK5, KLK 7 and KLK14 are able to degrade corneodesmosomes, which leads to desquamation of skin surface cells. KLK activation is believed to be mediated through highly organized proteolytic cascades, regulated through a series of feedback loops, inhibitors, auto-degradation and internal cleavages. Studies have shown that one potential physiological activator for KLK7 is KLK5. Along with KLK14, these three kallikreins form a proteolytic cascade in the stratum corneum. KLK7 is primarily expressed in the skin but is also detected at relatively high levels in esophagus, heart, liver, central nervous system, kidney, pancreas, mammary and salivary glands.
Name:Recombinant Mouse Kallikrein 7/KLK7 Protein (His Tag)
Size:10µg
Assay Genie SKU:RPES4873
Synonyms:Kallikrein-7; Klk7; Serine protease 6; Stratum corneum chymotryptic enzyme; Thymopsin; kallikrein-related peptidase 7; PRSS6; SCCEkallikrein-7;SCCE
Species:Mouse
Expression host:Human Cells
Sequence:Gln22-Arg249
Accession:Q91VE3
Mol Mass:26.1 kDa
AP Mol Mass:28-35 kDa
Tag:C-6His
Purity:> 95 % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per µg as determined by the LAL method.
Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20'C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 um filtered solution of 20mM HEPES,150mM NaCl,pH7.4.
Reconstitution:Please refer to it for detailed information.