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Antibody Name:
SEPT14 Antibody (PACO22588)
Antibody SKU:
PACO22588
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from C-terminal of human SEPT14.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from NIH/3T3 cells, using SEPT14 antibody.
Background:
Filament-forming cytoskeletal GTPase By similarity. May play a role in cytokinesis Potential.
SEPT14: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). Belongs to the septin family.Protein type: Cell cycle regulation; Cytoskeletal; HydrolaseChromosomal Location of Human Ortholog: 7p11.2Cellular Component: cytoskeleton; cytoplasmMolecular Function: protein binding; GTP bindingBiological Process: cell division; cell cycle
UniProt Protein Details:
NCBI Summary:
SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions (Peterson et al., 2007 [PubMed 17922164]).[supplied by OMIM, Jul 2008]