The SLC39A8 Polyclonal Antibody is a valuable tool for researchers studying the SLC39A8 protein, a crucial component in cellular zinc transport. This antibody, generated in rabbits, is highly specific to human samples and is ideal for use in Western blot applications. By binding to the SLC39A8 protein, researchers can easily detect and analyze its expression in a variety of cell types.SLC39A8 is known for its role in maintaining zinc homeostasis within cells, impacting a variety of biological processes such as growth, development, and immune function. Dysregulation of SLC39A8 has been implicated in various diseases including neurological disorders, metabolic conditions, and immune deficiencies.
Therefore, studying the function of SLC39A8 is essential for uncovering potential therapeutic targets for these diseases.With its high specificity and reliability, the SLC39A8 Polyclonal Antibody is a valuable tool for researchers across multiple fields including biochemistry, cell biology, and genetics. Its ability to accurately detect SLC39A8 expression makes it an essential component in studies focused on understanding the role of zinc transport in cellular physiology and disease pathogenesis.
Product Name:
SLC39A8 Polyclonal Antibody
SKU:
CAB22238
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC39A8 (NP_071437.3).
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Purification Method:
Affinity purification
Gene ID:
64116
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC39A8 antibody (CAB22238) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
