The TAS2R1 Polyclonal Antibody (PACO04507) is a key tool for research involving TAS2R1, a taste receptor responsible for detecting bitterness in food. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blot assays. By binding to the TAS2R1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential resource for studies in sensory biology and nutrition research.TAS2R1 is a crucial player in the perception of bitter tastes, functioning as a sensor that triggers signaling pathways in taste cells.
Understanding the role of TAS2R1 is vital for unraveling the mechanisms underlying taste perception and food preferences. Research on TAS2R1 can provide insights into individual differences in taste perception, as well as potential implications for dietary choices and health outcomes.Overall, the TAS2R1 Polyclonal Antibody is a valuable tool for researchers studying taste receptor biology and its implications for human health and nutrition. Its specificity and reliability make it an indispensable asset for investigations into taste perception, food preferences, and sensory processing.
Antibody Name:
TAS2R1 Antibody
Antibody SKU:
PACO04507
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human T2R1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TAS2R1; Taste receptor type 2 member 1; T2R1; Taste receptor family B member 7; TRB7
UniProt Protein Function:
TAS2R1: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, T2R family; Membrane protein, integralChromosomal Location of Human Ortholog: 5p15Cellular Component: integral to membrane; plasma membraneMolecular Function: bitter taste receptor activity; taste receptor activityBiological Process: chemosensory behavior; detection of chemical stimulus involved in sensory perception of bitter taste
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008]
