The ALGL Polyclonal Antibody (PAC063771) is a high-quality research tool designed for studying the AlgL protein, a key enzyme involved in alginate biosynthesis in Pseudomonas aeruginosa. This antibody, raised in rabbits, has been validated for use in various applications, including Western blot and immunohistochemistry.The AlgL protein is essential for the synthesis of alginate, an important component of the extracellular matrix in P. aeruginosa biofilms. By targeting the AlgL protein, researchers can gain valuable insights into the mechanisms of biofilm formation and potential therapeutic targets for combating P.
aeruginosa infections.This antibody is highly specific to the AlgL protein and has been tested for its reactivity with P. aeruginosa samples. Its reliability and specificity make it an excellent tool for researchers studying alginate biosynthesis, biofilm formation, and P. aeruginosa virulence mechanisms. With its versatility and proven performance in various research applications, the ALGL Polyclonal Antibody (PAC063771) is a valuable asset for studies in microbiology and infectious diseases.
Antibody Name:
algL Antibody (PACO63771)
Antibody SKU:
PACO63771
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Azotobacter vinelandii
Immunogen:
Recombinant Azotobacter vinelandii Alginate lyase protein (24-374AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: algL antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 62 kDa. Observed band size: 62 kDa.
Background:
Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. Splits ManA-ManA and ManA-GulA bonds, but not GulA-ManA or GulA-GulA bonds. Also cleaves acetylated residues. May serve to degrade mislocalized alginate that is trapped in the periplasmic space (By similarity).
Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. Splits ManA-ManA and ManA-GulA bonds, but not GulA-ManA or GulA-GulA bonds. Also cleaves acetylated residues (PubMed:9683471). May serve to degrade mislocalized alginate that is trapped in the periplasmic space ().
