The TCF4/TCF7L2 Polyclonal Antibody (CAB20770) is a high-quality antibody developed for reliable detection and analysis of target proteins. This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene. RRID Gene ID 6934 Swiss Prot Synonym TCF4; TCF-4; TCF4/TCF7L2
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
TCF4/TCF7L2 Polyclonal Antibody
SKU:
CAB20770
Size:
100μL, 20μL
Reactivity:
Human, Mouse
Clone Number:
-
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:100 - 1:500
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TCF4, TCF-4, TCF4/TCF7L2
Positive Sample:
SW620, Mouse brain
Cellular Localization:
Nucleoplasm, Nucleus, Pml Body.
Calculated MW:
68kDa
Observed MW:
60kDa/75kDa
This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene. RRID Gene ID 6934 Swiss Prot Synonym TCF4; TCF-4; TCF4/TCF7L2
Purification Method:
Affinity purification
Gene ID:
6934
RRID:
-
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using TCF4/TCF7L2 Rabbit pAb (CAB20770) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
