The CPO Antibody (PACO59700) offered by AssayGenie is a highly specific and sensitive tool for research involving CPO, a key enzyme involved in cellular metabolism. This polyclonal antibody is produced in-house using high-quality materials and is validated for use in various applications, including Western blotting and immunofluorescence.Used in studies related to cellular metabolism, oxidative stress, and aging, the CPO Antibody enables researchers to detect and quantify CPO protein levels in a variety of cell types and tissues. Its high reactivity with human samples ensures reliable and reproducible results, making it an essential tool for investigating the role of CPO in disease states such as cancer, neurodegenerative disorders, and metabolic diseases.
By targeting CPO, researchers can gain insights into the molecular mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention. The CPO Antibody from AssayGenie is a valuable asset for scientists conducting cutting-edge research in the fields of biochemistry, cell biology, and pharmacology.
Antibody Name:
CPO Antibody (PACO59700)
Antibody SKU:
PACO59700
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Carboxypeptidase O protein (21-101AA)
Immunofluorescence staining of HepG2 cells with PACO59700 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Carboxypeptidase which preferentially cleaves C-terminal acid, c residues from peptides and proteins. Can also cleave C-terminal hydrophobic amino acid, , with a preference for small residues over large residues.
Synonyms:
Carboxypeptidase O (CPO) (EC 3.4.17), CPO
UniProt Protein Function:
CPO: Probable carboxypeptidase which may cleave proteins with C-terminal acidic residues. Belongs to the peptidase M14 family.Protein type: EC 3.4.17.-; Secreted, signal peptide; Protease; SecretedChromosomal Location of Human Ortholog: 2q33.3Cellular Component: extracellular spaceMolecular Function: metallocarboxypeptidase activity
UniProt Protein Details:
NCBI Summary:
This gene is a member of the metallocarboxypeptidase gene family. [provided by RefSeq, Jan 2011]
