HMGN2 Antibody (PACO43288)
- SKU:
- PACO43288
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | HMGN2 Antibody (PACO43288) |
| Antibody SKU: | PACO43288 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Non-histone chromosomal protein HMG-17 protein (1-90AA) |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO43288 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO43288 at dilution of 1:100. |
| Background: | Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity). |
| Synonyms: | Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2), HMGN2, HMG17 |
| UniProt Protein Function: | HMGN2: Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation. Belongs to the HMGN family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 1p36.1 Cellular Component: cytoplasm; nucleus; chromatin Molecular Function:nucleosomal DNA binding |
| NCBI Summary: | The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014] |
| UniProt Code: | P05204 |
| NCBI GenInfo Identifier: | 123106 |
| NCBI Gene ID: | 3151 |
| NCBI Accession: | P05204.3 |
| UniProt Secondary Accession: | P05204,Q0VGD5, Q6FGI5, Q96C64, |
| UniProt Related Accession: | P05204 |
| Molecular Weight: | 90 |
| NCBI Full Name: | Non-histone chromosomal protein HMG-17 |
| NCBI Synonym Full Names: | high mobility group nucleosomal binding domain 2 |
| NCBI Official Symbol: | HMGN2 |
| NCBI Official Synonym Symbols: | HMG17 |
| NCBI Protein Information: | non-histone chromosomal protein HMG-17; high mobility group protein N2; nonhistone chromosomal protein HMG-17; high-mobility group nucleosomal binding domain 2; high-mobility group (nonhistone chromosomal) protein 17; high mobility group nucleosome-binding domain-containing protein 2 |
| UniProt Protein Name: | Non-histone chromosomal protein HMG-17 |
| UniProt Synonym Protein Names: | High mobility group nucleosome-binding domain-containing protein 2 |
| Protein Family: | Non-histone chromosomal protein |
| UniProt Gene Name: | HMGN2 |
| UniProt Entry Name: | HMGN2_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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