Human CD3G Recombinant Protein (RPPB3018)
- SKU:
- RPPB3018
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P09693
- Research Area:
- CD Antigens
Description
| Product Name: | Human CD3G Recombinant Protein |
| Product Code: | RPPB3018 |
| Size: | 5µg |
| Species: | Human |
| Target: | CD3G |
| Synonyms: | T-cell surface glycoprotein CD3 gamma chain, CD3-GAMMA, T3G, CD3G |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | CD3G protein solution (0.5mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADPQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATISHHH HHH |
| UniProt Code: | P09693� |
CD3-gamma polypeptide is encoded by CD3 Gamma (CD3G) which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, configures the T-cell receptor-CD3 complex. The T-cell receptor-CD3 complex takes part in coupling antigen recognition to numerous intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Deficiencies in this gene are associated with T cell immunodeficiency.
CD3G Human Recombinant�produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 103 amino acids (23-116 a.a.) and having a molecular mass of 11.8kDa (Molecular size on SDS-PAGE will appear at approximately 13.5-18kDa).CD3G is expressed with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
