Description
| Product Name: | Human CHODL Recombinant Protein |
| Product Code: | RPPB3179 |
| Size: | 20µg |
| Species: | Human |
| Target: | CHODL |
| Synonyms: | Chondrolectin, Transmembrane Protein MT75, C21orf68, Chromosome 21 Open Reading Frame 68, PRED12, MT75, CHODL. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The CHODL solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSFCRRVVS GQKVCFADFK HPCYKMAYFH ELSSRVSFQE ARLACESEGG VLLSLENEAE QKLIESMLQN LTKPGTGISD GDFWIGLWRN GDGQTSGACP DLYQWSDGSN SQYRNWYTDE PSCGSEKCVV MYHQPTANPG LGGPYLYQWN DDRCNMKHNY ICKYEPEINP TAPVEKPYLT NQPGDTHQNV VVTEAGIIPN |
Chondrolectin (CHODL) is a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. The CHODL protein localizes mainly to the perinuclear region.
CHODL Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 220 amino acids (22-216) and having a molecular mass of 24.6 kDa.CHODL is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance. |
| NCBI Summary: | This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Feb 2011] |
| UniProt Code: | Q9H9P2 |
| NCBI GenInfo Identifier: | 20127636 |
| NCBI Gene ID: | 140578 |
| NCBI Accession: | NP_079220 |
| UniProt Secondary Accession: | Q9H9P2,Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3, B2R9C0, B4DJB8 |
| UniProt Related Accession: | Q9H9P2 |
| Molecular Weight: | 28,418 Da |
| NCBI Full Name: | chondrolectin isoform a |
| NCBI Synonym Full Names: | chondrolectin |
| NCBI Official Symbol: | CHODL�� |
| NCBI Official Synonym Symbols: | MT75; PRED12; C21orf68�� |
| NCBI Protein Information: | chondrolectin |
| UniProt Protein Name: | Chondrolectin |
| UniProt Synonym Protein Names: | Transmembrane protein MT75 |
| Protein Family: | Chondrolectin |
| UniProt Gene Name: | CHODL�� |