Human Leuprorelin Recombinant Protein (RPPB1339)
- SKU:
- RPPB1339
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Hormones
Description
| Product Name: | Human Leuprorelin Recombinant Protein |
| Product Code: | RPPB1339 |
| Size: | 25mg |
| Species: | Human |
| Target: | Leuprorelin |
| Synonyms: | Leuprolide, Leuprorelin. |
| Source: | Synthetic |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | The Leuprorelin was lyophilized from a concentrated (1mg/ml) solution with no additives. |
| Solubility: | It is recommended to reconstitute the lyophilized Leoprolide in sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized Leoprolide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Leuprorelin should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 98.0% as determined by RP-HPLC. |
| Amino Acid Sequence: | pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt |
Leuprorelin (INN) or leuprolide acetate (USAN) is a gonadotropin-releasing hormone agonist (GnRH agonist).By causing constant stimulation of the pituitaryGnRH receptors, it initially causes stimulation (flare), but thereafter decreases pituitary secretion (downregulation) of gonadotropins luteinizing hormone(LH) and follicle-stimulating hormone(FSH).Like other GnRH agonists, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate canceror breast cancer, estrogen-dependent conditions (such as endometriosisor uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in IVF.
Leuprolide Human Synthetic is a single, non-glycosylated, polypeptide chain containing 9 amino acids and having a molecular mass of 1209 Dalton. The molecular formula is C59H84N16O12.
