The LAPB Antibody (PACO34786) is a polyclonal antibody that targets LAPB, a key protein involved in immune regulation and inflammation. This antibody, produced in rabbits, has been proven to be highly effective in detecting LAPB in human samples, making it an ideal tool for researchers studying immunology and inflammatory diseases.LAPB, also known as the immune inhibitory receptor, plays a crucial role in immune response modulation by regulating inflammatory pathways and inhibiting allergic reactions. Its presence in various cell types makes it a valuable target for investigating diseases like cancer, autoimmune disorders, and chronic inflammatory conditions.
By understanding the function of LAPB, researchers can develop potential therapies to modulate immune responses for the treatment of these diseases.The LAPB Antibody (PACO34786) is validated for use in Western blot applications, providing researchers with a reliable tool for studying LAPB protein expression and function. Its high reactivity and specificity make it a valuable asset in advancing our understanding of immune regulation and inflammation, ultimately leading to the development of novel therapeutic interventions.
Antibody Name:
lapB Antibody (PACO34786)
Antibody SKU:
PACO34786
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli Lipopolysaccharide assembly protein B protein (17-389AA)
Form:
Liquid
Storage Buffer:
Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2
Purification Method:
>95%, Protein G purified
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot. All lanes: lapB antibody at 1: 1000. Lane1: DH5alpha whole cell lysate at 10µg. Lane2: DH5alpha whole cell lysate at 1µg. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa.
Background:
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.
Synonyms:
Lipopolysaccharide assembly protein B (Lipopolysaccharide regulatory protein), lapB, yciM
UniProt Protein Function:
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.
UniProt Protein Details:
NCBI Summary:
YciM has six tandem TPR repeats that are usually involved in protein-protein interactions. [More information is available at EcoGene: EG12691].
