The NOM1 Polyclonal Antibody (PACO22482) is a valuable tool for researchers studying NOM1, a protein involved in RNA metabolism and ribosome biogenesis. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting and immunofluorescence applications. By binding to the NOM1 protein, this antibody allows for the visualization and analysis of NOM1 expression in a variety of cell types, making it an ideal choice for studies in molecular biology and genetics.
NOM1 is a key player in the regulation of ribosome assembly and function, making it essential for proper protein synthesis within cells. Dysregulation of NOM1 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting the importance of understanding its role in cellular processes. By investigating NOM1 expression and function, researchers can gain valuable insights into these disease mechanisms and potentially identify new therapeutic targets for intervention.
Antibody Name:
NOM1 Antibody (PACO22482)
Antibody SKU:
PACO22482
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from C-terminal of human NOM1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using NOM1 antibody.
Background:
Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008]
Synonyms:
Nucleolar MIF4G domain-containing protein 1; SGD1 homolog;
