p73 Transcription Factor Activity Assay

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SKU:
TFAB00148
€599

Description

ELISA Kit Technical ManualMSDS

p73 Transcription Factor activity assay

Product Description:The ELISA Genie p73 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates ELISA Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening.
Target Synonyms:p53-like transcription factor;p53-related protein
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:Human, Mouse, Rat
Pack Size:12 x 8-Well Microstrips
Detection Method:Colorimetric 450 nm
Format:transcription factor activity assay
Storage and Stability Guarantee:4°C/6 Months
Sample Type:Nuclear or cell lysates
Range:See Technical Manual
Time:4.5 hours

p73 Transcription Factor activity assay Protein Information

UniProt Protein Function:Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
NCBI Summary:This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011]
UniProt Code:O15350
NCBI GenInfo Identifier:8928244
NCBI Gene ID:7161
NCBI Accession:O15350.1
UniProt Secondary Accession:O15350,O15351, Q17RN8, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5 Q8TDY6, B7Z7J4, B7Z8Z1, B7Z9C1, C9J521,
UniProt Related Accession:O15350
Molecular Weight:61,694 Da
NCBI Full Name:Tumor protein p73
NCBI Synonym Full Names:tumor protein p73
NCBI Official Symbol:TP73
NCBI Official Synonym Symbols:P73
NCBI Protein Information:tumor protein p73
UniProt Protein Name:Tumor protein p73
UniProt Synonym Protein Names:p53-like transcription factor; p53-related protein
Protein Family:Tumor protein
UniProt Gene Name:TP73
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