The PLGRKT Antibody (PAC041358) is a polyclonal antibody designed for research involving PLGRKT, a protein with implications in various cellular functions. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in applications such as Western blotting. Its ability to bind to the PLGRKT protein allows for detection and analysis in a wide range of cell types, making it ideal for studies in cell biology, signal transduction, and disease mechanisms.
PLGRKT, also known as a potential regulator of cell growth, is involved in regulating cell proliferation, differentiation, and survival. Its role in cellular processes makes it a valuable target for research into diseases such as cancer, developmental disorders, and neurodegenerative conditions. Understanding the function of PLGRKT is essential for uncovering new insights into cellular pathways and potential therapeutic targets for a variety of diseases.
Western blot. All lanes: PLGRKT antibody at 6µg/ml. Lane 1: A431 whole cell lysate. Lane 2: Mouse lung tissue. Lane 3: NIH/3T3 whole cell lysate. Lane 4: U251 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 18 kDa. Observed band size: 18 kDa.
Immunohistochemistry of paraffin-embedded human skin tissue using PACO41358 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO41358 at dilution of 1:100.
Background:
Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metallproteinase activation, such as of MMP2 and MMP9.
PLGRKT: Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metallproteinase activation, such as of MMP2 and MMP9.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 9p24.1Cellular Component: integral to plasma membrane; mitochondrionMolecular Function: protein bindingBiological Process: chemotaxis; inflammatory response
