CAs (carbonic anhydrases) are zinc metalloenzymes that catalyse the reversible hydration of carbon dioxide. They assist with respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humour, cerebrospinal fluid, saliva, and gastric acid. They exhibit a broad range of tissue dispersion and subcellular localization. It is predicted that the CA XIV protein will be a type I membrane protein with the greatest sequence overlap with other transmembrane CA isoforms. Renal tubular acidosis and 3-Methylglutaconic Aciduria, Type Vii are all diseases linked to Carbonic anhydrase 14/CA14. Carbonic anhydrase 14/CA14 is involved in two different processes: reversible carbon dioxide hydration and metabolism.Carbonic Anhydrase 14/CA14 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Carbonic Anhydrase 14/CA14 Recombinant Protein (RPES4205)
Recombinant Human Carbonic Anhydrase 14 is produced by our E.coli expression system and the target gene encoding Gly19-Met290 is expressed with a 6His tag at the N-terminus.
Purity:
> 85 % as determined by reducing SDS-PAGE.
Mol Mass:
32.8 kDa
AP Mol Mass:
40 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM Tris, 150mM NaCl, 10% Glycerol, pH 8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
